Page 8 - Rivista SIMG 1 - Maggio 2023 - web

Adjusted hazard ratio Adjusted hazard ratio
(95% CI) (95% CI)

Two vaccine doses v one dose 0.17 (0.13 to 0.22)
Male patients v female patients 1.89 (1.72 to 2.08)
Townsend deprivation (5 unit increase) score 1.27 (1.17 to 1.37)
White 1
Indian 1.59 (1.16 to 2.18)
Pakistani 2.28 (1.59 to 3.27)
Bangladeshi 0.95 (0.47 to 1.93)
Other Asian 1.15 (0.65 to 2.04)
Caribbean 0.70 (0.42 to 1.17)
Black African 0.45 (0.17 to 1.21)
Chinese 0.43 (0.08 to 2.39)
Other ethnic group 0.83 (0.51 to 1.34)

Not in care home or homeless 1
Lives in care home 4.14 (3.66 to 4.68)
Homeless 2.05 (0.29 to 14.58)

No kidney failure 1
CKD stage 3 1.23 (1.12 to 1.36)
CKD stage 4 1.96 (1.56 to 2.46)
CKD stage 5 2.81 (2.08 to 3.80)
CKD stage 5 (dialysis) 2.33 (0.75 to 7.25)
CKD stage 5 (transplantation) 8.07 (3.34 to 19.54)

No chemoterapy in past year 1
Chemoterapy grade A 0.96 (0.49 to 1.85)
Chemoterapy grade B 3.63 (2.57 to 5.12)
Chemoterapy grade C 4.30 (1.06 to 17.51)

No type 2 diabetes 1
Type 2 HbA <59 mmol/mol 1.26 (1.12 to 1.42)
1C
Type 2 HbA ≥59 mmol/mol 1.43 (1.12 to 1.70)
1C
Blood cancer 1.42 (1.09 to 1.85)
Bone marrow or solid organ transplantation 2.49 (0.62 to 10.08)
Respiratory tract cancer 1.65 (1.13 to 2.39)
Radiotherapy in past 6 months 2.62 (1.65 to 4.15)
Down’s syndrome 12.68 (4.68 to 34.38)
Chronic obstructive pulmonary disease 1.52 (1.33 to 1.73)
Coronary heart disease 1.18 (1.07 to 1.32)
Stroke 1.21 (1.08 to 1.36)
Atrial fibrillation 1.15 (1.03 to 1.28)
Congestive cardiac failure 1.43 (1.25 to 1.63)
Thromboembolism 1.45 (1.26 to 1.67)
Peripheral vascular disease 1.31 (1.09 to 1.57)
Dementia 2.23 (1.98 to 2.50)
Parkinson’s disease 2.23 (1.79 to 2.78)
Epilepsy 1.13 (0.85 to 1.50)
Rare neurological conditions 2.63 (1.69 to 4.08)
Liver cirrhosis 2.96 (2.02 to 4.34)
Schizophrenia or bipolar disorder 1.12 (0.77 to 1.63)
Sickle cell disease 7.73 (1.07 to 55.83)
HIV/AIDS 3.29 (1.05 to 10.29)
Severe combined immunodeficiency 1.31 (0.33 to 5.27)

0.0625 0.25 1 4 16 64

Figura 1 - Hazar Ratio corretti per morte da COVID-19 dopo vaccinazione.
Adattato da Hippisley-Cox J et al BMJ 374:n2244. doi: 10.1136/bmj.n2244.

Rivista Società Italiana di Medicina Generale n. 1 • 2023 7